What is importance Isolator integrity test or Isolator Chamber leak test?

• Is also called glove integrity testing system.
• Gloves or half-suits is the most critical parts of an isolator.
• Is used to test glove integrity in conformity with the pressure decay method ISO 14644-7, Annex E.5(test in positive pressure).
• The glove testing unit only needs compressed air supply used to blow the gloves.
• This leak test of an isolator chamber using a dedicated glove flange cover equipped with a differential pressure transmitter and temperature sensor.
• In isolator technology the loss of glove integrity or accidental introduction of material that has not been decontaminated are among the most probable causes of detectable microbial contamination.
• Very small leaks in glove are difficult to detect until the glove is
  stretched during use.
• they are several commercially available glove leak test  detectors.
  
• Continuous nonviable particle monitoring within the isolator enclosure is ideal, because it can quickly detect filter failure.
• Viable monitoring results take a more time.
• A pair of sterile gloves is frequently worn under the isolator gloves.
•  Isolator glove can provide a additional level of safety against glove leaks or can act as hygienic measure.

Related : Isolator Technology