How to Calculate Log Reduction in Pharmaceutical Microbiology: Step-by-Step Guide with Examples
In pharmaceutical microbiology, maintaining a sterile environment and ensuring microbial control is essential for product safety and regulatory compliance. One of the most widely used parameters to evaluate the effectiveness of microbial reduction methods—such as disinfectants, sterilization processes, and sanitization—is log reduction . Log reduction expresses how effectively a process or product reduces the microbial load , helping microbiologists and quality professionals assess the performance of their disinfection or sterilization methods. This guide explains the meaning, calculation, significance, and practical examples of log reduction in pharmaceutical microbiology. You’ll also find ready-to-use formulas and examples that can be directly applied in your lab or documentation. 🔹 What is Log Reduction? Log reduction is a mathematical expression of the decrease in the number of microorganisms after a sterilization or disinfection process. It is expressed in “logs,” ...